A simple, fast program which transcribes a DNA strand into messenger RNA (mRNA), which it then translates into amino acids.
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#This program turns a strand of DNA into mRNA, which is then converted into amino acids using a codon chart
#MIT License as usual
#Ravi Shah 2020
from amino_acids import codons_to_acids
stop_index = "NaN"
def find_stop(mrna):
if "UAA" in mrna:
print("UAA STOP codon found")
stop_index = mrna.index("UAA")
elif "UAG" in mrna:
print("UAG STOP codon found")
stop_index = mrna.index("UAG")
elif "UGA" in mrna:
print("UGA STOP codon found")
stop_index = mrna.index("UGA")
else:
print("No STOP codon found. Exiting...")
quit()
return stop_index
def transcription(dna):
res = []
newlist = []
res[:] = dna
for i in res:
if i == "G":
newlist.append("C")
elif i == "C":
newlist.append("G")
elif i == "A":
newlist.append("U")
elif i == "T":
newlist.append("A")
mrna_strand = ''.join(newlist)
return mrna_strand
def start_to_stop(mrna):
global stop_index
try:
start_index = mrna.index("AUG")
inter_rna = mrna[start_index:]
stop_index = find_stop(inter_rna)
final_rna = inter_rna[0:stop_index+3]
return(final_rna)
except:
print("Please enter a valid DNA strand with a start and stop codon")
quit()
def translation(final_rna):
print("The mRNA strand is:", final_rna)
n = 3
res = [final_rna[i:i+n] for i in range(0, len(final_rna), n)]
print("The codons are:", res)
list_of_amino_acids = codons_to_acids(res)
print("There are", len(list_of_amino_acids), "amino acids translated from this mRNA strand.")
return list_of_amino_acids
strand = input("Enter the DNA strand to be transcribed and translated: ")
strand = strand.upper()
messenger_rna = transcription(strand)
truncated = start_to_stop(messenger_rna)
if len(truncated) % 3 != 0:
print("The mRNA strand isn't divisible by 3.")
quit()
print(translation(truncated))